The game was set up nicely after the 1-1 first-leg draw in Russian Federation, with the Red Devils the clear favourites to progress.
Jose Mourinho's side booked their place in the quarter-finals thanks to Juan Mata's goal, and Pogba was substituted for Marouane Fellaini just after half-time. It's bad for us because all the five teams in front of us in the Premier League nobody has global football so they will playing one game a week like some of them have been since the start of the season.
Anthony Martial will not be available for Manchester United's Europa League clash with FC Rostov, despite training on Wednesday.
Manchester United were looking to get back to winning ways after their disappointing 1-0 loss to Chelsea in the quarter-finals of the FA Cup on Monday night.
Ibrahimovic was involved again 11 minutes later when he latched onto the end of a ball over the top from Mata, but after attempting to round Medvedev, his finish from a tight angle was deflected over the bar by the hand of the Rostov keeper.
Trump meeting with Chinese President Xi expected next month, official says
Ning also said power generation rose 6.3 per cent year on year in the first two months, and freight volume was up 6.9 per cent. China, on the other hand, is one of Pyongyang's biggest allies but has become increasingly anxious about its erratic neighbor.
Rostov barely threatened in the opening exchanges but they almost took the lead in the second half when Sardar Azmoun forced a save from United stopper Sergio Romero.
The Reds had to make another enforced adjustment as Blind came off shortly after receiving treatment, with Phil Jones entering the fray and Marcos Rojo switching to left wing-back.
Medvedev reached a good Daley Blind cross just ahead of Paul Pogba on 21 minutes before the French midfielder fired wildly over the target after some good approach play.
United seized control of the game from the very start, and were unfortunate not to take the lead within five minutes. Four of those goals have been scored at Old Trafford.
The visitors still needed only a goal to take the game into extra time, though fortunately Romero wanted extra time as much as the rest of us stood watching.